Here are some numbers on the best spots for hitters and pitchers this season on pitches IN the zone:
Middle/Middle pitches do not have good results for pitchers. This should go without saying, but hitters tend to be ready for those pitches and the numbers back it up. It has the best AVG, SLG, K Rate, and Well-Hit Rate.
Up/Away shows a very interesting strikeout rate. There are 406 strikeouts this season in that location with 316 of them coming on either a fastball or a cutter. Despite that, the highest strikeout rate comes on breaking pitches in that up/away location at 33.3% (73 strikeouts in 219 at-bats).
There are 140 walks that have been issued on pitches in the zone this season. Which location has the most? Down and in has 33 walks associated with the location but up and away has the highest walk rate (2.4%).
Umpires have the most difficulty with taken pitches on the corners of the zone but two stand out. Up and in (75.7% called strike rate) and up and away (78.1% called strike rate) are the two locations that have a called strike rate under 80%. Umpires are 100% in calling strikes on pitches middle middle this season.